Uremia has a lots of complications, so what are the effects of uremia on metabolism?
1. Disturbance of glucose metabolism
In uremic patients, blood glucose is slightly elevated, which is different from the pathogenesis of diabetes, diabetes is absolutely or relatively insufficient insulin secretion, while in uremic patients, hyperglycemia is mainly due to decreased cell sensitivity to insulin.
According to reports, uremic patients with endogenous insulin secretion is normal, intake of exogenous insulin in the body to maintain a higher level than normal people, because insulin in uremic patients can maintain a longer time, chronic diabetes patients, once uremia occurs, insulin dosage can be reduced.
2. Protein metabolism disorders
Protein metabolism produces nitrogen waste, which is accumulated outside the body, and blood urea nitrogen is increased. Therefore, in the treatment of uremia, generally limit protein intake, malnutrition, long-term hemodialysis patients, protein intake restrictions can be relaxed slightly, uremia patients with abnormal serum amino acid content, some serum amino acid concentration can be 2-3 times higher than normal people.
On the other hand, the content of essential amino acids in serum may be lower than that in normal people, and the deficiency of essential amino acids may have a great impact on the reconstruction of autologous tissue.
3. Abnormal lipid metabolism
The effect of uremia on lipid metabolism has not been studied extensively. It is known that in most dialysis patients, serum triglycerides and free fatty acids are elevated, and serum cholesterol and phospholipids are generally normal.
How to adjust the disorder of metabolism?
In China, more and more uremia patients take the alternative treatments, for example, Micro-Chinese Medicine Osmotherapy is widely used in the populations. Various of chinese herbal medicines used in the treatments, which can supply enough nutrients and oxygen to damaged kidney, expend blood vessels, improve blood circulations, promote the metabolism, so all the complications can be relieved in 10-15 days.
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