Patients with the following characteristics are glomerular diseases:① glomerular proteinuria (mainly albumin) with urinary and / or glomerular hematuria; ② renal manifestations of hypertension and Edema; ③ glomerular filtration function damage before and more important than renal tubular dysfunction
.Primary glomerular disease clinical classification:
(A) acute glomerulonephritis (referred to as acute nephritis) 1. Anxious onset, severity varies. 2. Generally hematuria (microscopic and naked eye hematuria), proteinuria, may have tubular urine (such as red blood cell tube, tube tube, etc.). Often high blood pressure and sodium and sodium retention symptoms (such as edema, etc.), sometimes short-term azotemia. B-check the kidneys without shrinkage. 3. Some cases of acute streptococcus or other pathogenic microorganisms precursor infection history, more than 1-4 weeks after infection onset. 4. Most of the prognosis is good, usually recovered in a few months.
(B) Acute nephritis
1. Acute onset, the disease, the rapid progress, more in the onset of weeks or months of severe renal damage occurred.
2. Generally have obvious edema, hematuria, proteinuria, tubular urine, etc., are also often high blood pressure and rapid development of anemia, may have nephrotic syndrome performance.
3. Renal damage was progressive increase, there may be oliguria or anuria. Such as the condition failed to get timely and effective control, often in a few weeks to several months to replac.
(C) Chronic nephritis
1. Slow onset, disease progression, clinical manifestations can be light and heavy. With the development of the disease, may have renal dysfunction, anemia, electrolyte disorders, etc. appear.
2. May have edema, hypertension, proteinuria, hematuria and tubular urine and other performance in a (such as hematuria or proteinuria) or a few. Clinical manifestations of a variety, sometimes associated with nephrotic syndrome or severe high blood pressure.
3. Course of nephritis may have an acute attack, often due to infection (such as respiratory infections) induced, attack similar to the performance of acute nephritis. Some cases can be automatically relieved, and some cases of exacerbations.
(D) Occult glomerular disease
1. No acute, chronic nephritis or other kidney disease history, renal function was normal.
2. No obvious clinical symptoms, signs, and the performance of simple proteinuria or (and) glomerular hematuria.
3. Can exclude non-glomerular hematuria or functional hematuria.
4. To mild proteinuria-based, urinary protein quantitative <1.0g / 24h, but no other abnormalities, can be called simple proteinuria. To continue or discontinuous microscopic hematuria-based, no other abnormalities, phase contrast microscopic examination of abnormal urine cells can be called simple hematuria.
(E) nephrotic syndrome.
1. Large amounts of proteinuria (> 3.5g / 24h);
2. Hypoproteinemia (serum albumin <30g / h);
3. Obvious edema;
Tag: Diagnostic Criteria