Among the complications of diabetes mellitus, Diabetic Nephropathy is one of the most serious chronic complications. It is mainly caused by the abnormal glucose metabolism of diabetic glomerulosclerosis, the urine protein content exceeds the normal value, so it is also one of the most important microvascular complications of diabetes. In the early stage, the patients can show the hypertrophy of the glomeruli and the thickening of the basement membrane. With the development of the disease, the body will have complicated metabolic disorders and eventually lead to renal failure.
How can we distinguish the effect of diabetic nephropathy on the body?
Because of the increase of blood sugar, the patient appears polydipsia and polyuria. When the urination is increased, the metabolism of water and salt in the body is disturbed and the thirst center of the hypothalamus is excited. Although a lot of water is used in the patients, there is still a phenomenon of thirst. At the same time, the lack of water in the body will lead to dry skin and even dehydration. Accompanied by symptoms of loss of appetite, or nausea, nausea and other discomfort. If these symptoms occur, should seek medical examination in time for specific causes, avoid disorderly medication and delayed illness, so as not to miss the best time for treatment.
Clinical manifestation of diabetic nephropathy.
With the development of diabetic nephropathy, the symptoms also change. In the early stage of diabetic nephropathy, glomerular filtration rate is increased, which can be manifested as glomerular hypertrophy and increased renal volume. With the development of the disease, the urine protein content is much more than the normal value in the later period. At this time, the decrease of plasma colloid osmotic pressure is caused by the decrease of plasma protein value, and the symptoms of edema appear. At the same time, as the urine protein content increased, the incidence of hypertension increased, and in patients with type II diabetic nephropathy, there were more hypertension than type I diabetes. When the patient continues to appear proteinuria, with the development of the severity of the disease, there will be azidemia after the kidney damage. If the condition is not controlled, it will eventually develop into uremia, and the injury to the body is very large.
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