Should IgA Nephropathy Patients Ask Cure By Medicines

Time :Apr 20, 2019    Views :169

Cure By Medicines,IgA NephropathyUsually, the treatment outcome of Chronic Kidney Disease is nothing more than complete cure, clinical cure, improvement, stability and aggravation.

For the vast majority of kidney disease patients, the probability of complete cure (radical cure) is very low, mainly after scientific treatment, the disease is clinically cured, improved, stable, of course, there are also deteriorated into renal failure, uremia.

It can also be seen that chronic kidney disease is generally difficult to cure. In this case, nephropathy patients are still pursuing the target of complete negative?

In fact, there is no complete reciprocal relationship between nephropathy indicators and radical nephropathy treatment, because there are obvious differences in pathological types, disease stages, disease stages and other indicators of different patients, so the requirements of indicators after treatment are also different. Now let me give you some clinical examples:

1.IgA Nephropathy

For example, after treatment in an IgA nephropathy patient, serum creatinine recovered completely, urinary protein was less than 0.5g, blood pressure and blood lipid were normal. Although urinary protein has not completely turned negative, but to this extent, the risk of renal failure is very low, there is no need to increase the use of drugs to luxury indicators completely turned negative.

2. Lupus Nephritis

A female patient with systemic lupus erythematosus complicated with lupus nephritis was once diagnosed as "type IV lupus, lupus active phase". The patient presented with a large amount of urinary protein (plasma albumin significantly decreased), creatinine increased. After treatment, creatinine decreased to normal level, lupus activity was controlled, and urinary protein decreased, but 24-hour urinary protein quantification was still around 1.0g.

For this patient, even though the urinary protein index has not completely turned negative, the therapeutic purpose of the disease has been achieved, and the use of hormone drugs has been too large. If only to reduce protein and increase the dosage of drugs, the resulting drug toxicity and side effects will increase the risk of renal failure, and the treatment will not pay off.

3. Minimal Change Disease or Membranous Nephropathy

The same situation applies to patients with minimal change nephropathy or membranous nephropathy, such patients are generally very sensitive to hormones, after the use of hormones urinary protein can turn negative in a short time, clinical cure. It's just that when hormones are reduced or even stopped for a period of time, urinary protein repeats. Sometimes, the idea of simply pursuing negative indicators may be too radical.

The aim of treatment of chronic kidney disease is not how many times the index turns negative or how many "+" decreases. What we want to pursue is that the kidney disease does not recur.

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